Read the Knowledge Base article on How Do I Manage Outlook 2016 For Mac Profiles for more information. Note: we recommen d creating a new profile before setting up a new account. When a new version of macOS is released, the Office 2019 for Mac Operating System requirements are updated such that the three most recent versions are supported: the new version of macOS and the two previous versions. Note: Outlook for Mac is supported on the three most recent versions of macOS. Outlook 2019 supports Exchange 2013 or higher version. Outlook 2016 supports Exchange 2010 or higher version.